A large family of Dscam genes with tandemly arrayed 5′ cassettes in Chelicerata

Drosophila Dscam1 (Down Syndrome Cell Adhesion Molecules) and vertebrate clustered protocadherins (Pcdhs) are two classic examples of the extraordinary isoform diversity from a single genomic locus. Dscam1 encodes 38,016 distinct isoforms via mutually exclusive splicing in D. melanogaster, while the...

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Pubblicato in:Nat Commun
Autori principali: Yue, Yuan, Meng, Yijun, Ma, Hongru, Hou, Shouqing, Cao, Guozheng, Hong, Weiling, Shi, Yang, Guo, Pengjuan, Liu, Baoping, Shi, Feng, Yang, Yun, Jin, Yongfeng
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4835542/
https://ncbi.nlm.nih.gov/pubmed/27080167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11252
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