Modeling Cystic Fibrosis Using Pluripotent Stem Cell-Derived Human Pancreatic Ductal Epithelial Cells

We established an efficient strategy to direct human pluripotent stem cells, including human embryonic stem cells (hESCs) and an induced pluripotent stem cell (iPSC) line derived from patients with cystic fibrosis, to differentiate into pancreatic ductal epithelial cells (PDECs). After purification,...

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Detalhes bibliográficos
Publicado no:Stem Cells Transl Med
Main Authors: Simsek, Senem, Zhou, Ting, Robinson, Christopher L., Tsai, Su-Yi, Crespo, Miguel, Amin, Sadaf, Lin, Xiangyi, Hon, Jane, Evans, Todd, Chen, Shuibing
Formato: Artigo
Idioma:Inglês
Publicado em: AlphaMed Press 2016
Assuntos:
Pluripotent Stem Cells
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4835252/
https://ncbi.nlm.nih.gov/pubmed/27034411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5966/sctm.2015-0276
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