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Critical appraisal of eculizumab for atypical hemolytic uremic syndrome

The biology of atypical hemolytic uremic syndrome has been shown to involve inability to limit activation of the alternative complement pathway, with subsequent damage to systemic endothelial beds and the vasculature, resulting in the prototypic findings of a thrombotic microangiopathy. Central to t...

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Détails bibliographiques
Publié dans:J Blood Med
Auteurs principaux: Palma, Lilian M Pereira, Langman, Craig B
Format: Artigo
Langue:Inglês
Publié: Dove Medical Press 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4835139/
https://ncbi.nlm.nih.gov/pubmed/27110144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/JBM.S36249
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