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NOTCH1 and SOX10 are Essential for Proliferation and Radiation Resistance of Cancer Stem-like Cells in Adenoid Cystic Carcinoma

PURPOSE: While the existence of CSC in ACC has been proposed, lack of assays for their propagation and uncertainty about molecular markers prevented their characterization. Our objective was to isolate CSC from ACC and provide insight into signaling pathways that support their propagation. EXPERIMEN...

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Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: Panaccione, Alex, Chang, Michael T., Carbone, Beatrice E., Guo, Yan, Moskaluk, Christopher A., Virk, Renu K., Chiriboga, Luis, Prasad, Manju L., Judson, Benjamin, Mehra, Saral, Yarbrough, Wendell G., Ivanov, Sergey V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4834904/
https://ncbi.nlm.nih.gov/pubmed/27084744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-15-2208
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