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Development of rAAV2-CFTR: History of the First rAAV Vector Product to be Used in Humans
The first human gene therapy trials using recombinant adeno-associated virus (rAAV) vectors were performed in cystic fibrosis (CF) patients. Over 100 CF patients were enrolled in 5 separate trials of rAAV2-CFTR administration via nasal, endobronchial, maxillary sinus, and aerosol delivery. Recombina...
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| Izdano u: | Hum Gene Ther Methods |
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| Glavni autori: | , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Mary Ann Liebert, Inc.
2016
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4834522/ https://ncbi.nlm.nih.gov/pubmed/26895204 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hgtb.2015.150 |
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