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Genomic DNA hypomethylation and risk of renal cell carcinoma: A case-control study

PURPOSE: Genomic DNA hypomethylation is a hallmark of most cancer genomes, promoting genomic instability and cell transformation. In the present study, we sought to determine whether global DNA methylation in peripheral blood is associated with risk of renal cell carcinoma (RCC). EXPERIMENTAL DESIGN...

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Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: Mendoza-Pérez, Julia, Gu, Jian, Herrera, Luis A., Tannir, Nizar M., Matin, Surena F., Karam, Jose A., Huang, Maosheng, Chang, David W., Wood, Christopher G., Wu, Xifeng
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4834236/
https://ncbi.nlm.nih.gov/pubmed/26655847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-15-0977
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