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Tumor Cells Surviving Exposure to Proton or Photon Radiation Share a Common Immunogenic Modulation Signature, Rendering Them More Sensitive to T Cell-Mediated Killing

PURPOSE: This study was designed to provide the foundation for combining immunotherapy to induce tumor antigen-specific T cells with proton radiation therapy to exploit the activity of those T cells. We have recently defined “immunogenic modulation,” a mechanism distinct from immunogenic cell death,...

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Detalhes bibliográficos
Publicado no:Int J Radiat Oncol Biol Phys
Main Authors: Gameiro, Sofia R., Malamas, Anthony S., Bernstein, Michael B., Tsang, Kwong Y., Vassantachart, April, Sahoo, Narayan, Tailor, Ramesh, Pidikiti, Rajesh, Guha, Chandan P., Hahn, Stephen M., Krishnan, Sunil, Hodge, James W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4834148/
https://ncbi.nlm.nih.gov/pubmed/27084634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijrobp.2016.02.022
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