Physical characterization and in silico modeling of inulin polymer conformation during vaccine adjuvant particle formation

This study combined physical data from synchrotron SAXS, FTIR and microscopy with in-silico molecular structure predictions and mathematical modeling to examine inulin adjuvant particle formation and structure. The results show that inulin polymer chains adopt swollen random coil in solution. As pre...

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Veröffentlicht in:Carbohydr Polym
Hauptverfasser: Barclay, Thomas G., Rajapaksha, Harinda, Thilagam, Alagu, Qian, Gujie, Ginic-Markovic, Milena, Cooper, Peter D., Gerson, Andrea, Petrovsky, Nikolai
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4834147/
https://ncbi.nlm.nih.gov/pubmed/27083349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.carbpol.2016.01.062
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