p38α MAPK Regulates Lineage Commitment and OPG Synthesis of Bone Marrow Stromal Cells to Prevent Bone Loss under Physiological and Pathological Conditions

Bone marrow-derived mesenchymal stromal cells (BM-MSCs) are capable of differentiating into osteoblasts, chondrocytes, and adipocytes. Skewed differentiation of BM-MSCs contributes to the pathogenesis of osteoporosis. Yet how BM-MSC lineage commitment is regulated remains unclear. We show that ablat...

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Detalhes bibliográficos
Publicado no:Stem Cell Reports
Main Authors: Cong, Qian, Jia, Hao, Biswas, Soma, Li, Ping, Qiu, Shoutao, Deng, Qi, Guo, Xizhi, Ma, Gang, Ling Chau, Jenny Fang, Wang, Yibin, Zhang, Zhen-Lin, Jiang, Xinquan, Liu, Huijuan, Li, Baojie
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4834033/
https://ncbi.nlm.nih.gov/pubmed/26947973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2016.02.001
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