Adipose natural killer cells regulate adipose tissue macrophages to promote insulin resistance in obesity

Obesity-induced inflammation mediated by immune cells in adipose tissue appears to participate in the pathogenesis of insulin resistance. We show that natural killer (NK) cells in adipose tissue play an important role. High fat diet (HFD) increases NK cell numbers and the production of pro-inflammat...

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Pubblicato in:Cell Metab
Autori principali: Lee, Byung-Cheol, Kim, Myung-Sunny, Pae, Munkyong, Yamamoto, Yasuhiko, Eberlé, Delphine, Shimada, Takeshi, Kamei, Nozomu, Park, Hee-Sook, Sasorith, Souphatta, Woo, Ju Rang, You, Jia, Mosher, William, Brady, Hugh J. M., Shoelson, Steven E., Lee, Jongsoon
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4833527/
https://ncbi.nlm.nih.gov/pubmed/27050305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2016.03.002
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