Adipose natural killer cells regulate adipose tissue macrophages to promote insulin resistance in obesity

Obesity-induced inflammation mediated by immune cells in adipose tissue appears to participate in the pathogenesis of insulin resistance. We show that natural killer (NK) cells in adipose tissue play an important role. High fat diet (HFD) increases NK cell numbers and the production of pro-inflammat...

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Detalhes bibliográficos
Publicado no:Cell Metab
Main Authors: Lee, Byung-Cheol, Kim, Myung-Sunny, Pae, Munkyong, Yamamoto, Yasuhiko, Eberlé, Delphine, Shimada, Takeshi, Kamei, Nozomu, Park, Hee-Sook, Sasorith, Souphatta, Woo, Ju Rang, You, Jia, Mosher, William, Brady, Hugh J. M., Shoelson, Steven E., Lee, Jongsoon
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4833527/
https://ncbi.nlm.nih.gov/pubmed/27050305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2016.03.002
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