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Nonlinear Dynamics in Gene Regulation Promote Robustness and Evolvability of Gene Expression Levels
Cellular phenotypes underpinned by regulatory networks need to respond to evolutionary pressures to allow adaptation, but at the same time be robust to perturbations. This creates a conflict in which mutations affecting regulatory networks must both generate variance but also be tolerated at the phe...
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| Publicado en: | PLoS One |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Public Library of Science
2016
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4833316/ https://ncbi.nlm.nih.gov/pubmed/27082741 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0153295 |
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