Structure of Type IIL Restriction-Modification Enzyme MmeI in Complex with DNA Has Implications for Engineering New Specificities

The creation of restriction enzymes with programmable DNA-binding and -cleavage specificities has long been a goal of modern biology. The recently discovered Type IIL MmeI family of restriction-and-modification (RM) enzymes that possess a shared target recognition domain provides a framework for eng...

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Gepubliceerd in:PLoS Biol
Hoofdauteurs: Callahan, Scott J., Luyten, Yvette A., Gupta, Yogesh K., Wilson, Geoffrey G., Roberts, Richard J., Morgan, Richard D., Aggarwal, Aneel K.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2016
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4833311/
https://ncbi.nlm.nih.gov/pubmed/27082731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1002442
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