Nanoscopic insights into seeding mechanisms and toxicity of α-synuclein species in neurons

New strategies for visualizing self-assembly processes at the nanoscale give deep insights into the molecular origins of disease. An example is the self-assembly of misfolded proteins into amyloid fibrils, which is related to a range of neurodegenerative disorders, such as Parkinson's and Alzhe...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Pinotsi, Dorothea, Michel, Claire H., Buell, Alexander K., Laine, Romain F., Mahou, Pierre, Dobson, Christopher M., Kaminski, Clemens F., Kaminski Schierle, Gabriele S.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2016
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4833232/
https://ncbi.nlm.nih.gov/pubmed/26993805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1516546113
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