Human longevity is influenced by many genetic variants: evidence from 75,000 UK Biobank participants

Variation in human lifespan is 20 to 30% heritable in twins but few genetic variants have been identified. We undertook a Genome Wide Association Study (GWAS) using age at death of parents of middle-aged UK Biobank participants of European decent (n=75,244 with father's and/or mother's dat...

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Publicat a:Aging (Albany NY)
Autors principals: Pilling, Luke C., Atkins, Janice L., Bowman, Kirsty, Jones, Samuel E., Tyrrell, Jessica, Beaumont, Robin N., Ruth, Katherine S., Tuke, Marcus A., Yaghootkar, Hanieh, Wood, Andrew R., Freathy, Rachel M., Murray, Anna, Weedon, Michael N., Xue, Luting, Lunetta, Kathryn, Murabito, Joanne M., Harries, Lorna W., Robine, Jean-Marie, Brayne, Carol, Kuchel, George A., Ferrucci, Luigi, Frayling, Timothy M., Melzer, David
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2016
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4833145/
https://ncbi.nlm.nih.gov/pubmed/27015805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.100930
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