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Functional Pairing of Class B1 Ligand-GPCR in Cephalochordate Provides Evidence of the Origin of PTH and PACAP/Glucagon Receptor Family

Several hypotheses have been proposed regarding the origin and evolution of the secretin family of peptides and receptors. However, identification of homologous ligand–receptor pairs in invertebrates and vertebrates is difficult because of the low levels of sequence identity between orthologs of dis...

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Detalhes bibliográficos
Publicado no:Mol Biol Evol
Main Authors: On, Jason S.W., Duan, Cumming, Chow, Billy K.C., Lee, Leo T.O.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4833073/
https://ncbi.nlm.nih.gov/pubmed/25841489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/msv087
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