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Maximum-Likelihood Phylogenetic Inference with Selection on Protein Folding Stability

Despite intense work, incorporating constraints on protein native structures into the mathematical models of molecular evolution remains difficult, because most models and programs assume that protein sites evolve independently, whereas protein stability is maintained by interactions between sites....

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Detalhes bibliográficos
Publicado no:Mol Biol Evol
Main Authors: Arenas, Miguel, Sánchez-Cobos, Agustin, Bastolla, Ugo
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4833071/
https://ncbi.nlm.nih.gov/pubmed/25837579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/msv085
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