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Maximum-Likelihood Phylogenetic Inference with Selection on Protein Folding Stability

Despite intense work, incorporating constraints on protein native structures into the mathematical models of molecular evolution remains difficult, because most models and programs assume that protein sites evolve independently, whereas protein stability is maintained by interactions between sites....

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Bibliographic Details
Published in:Mol Biol Evol
Main Authors: Arenas, Miguel, Sánchez-Cobos, Agustin, Bastolla, Ugo
Format: Artigo
Language:Inglês
Published: Oxford University Press 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4833071/
https://ncbi.nlm.nih.gov/pubmed/25837579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/msv085
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