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Determination of Hepatotoxicity and Its Underlying Metabolic Basis of 1,2-Dichloropropane in Male Syrian Hamsters and B6C3F1 Mice

1,2-Dichloropropane (1,2-DCP) has recently been reclassified from not classifiable as to its carcinogenicity to humans (Group 3) to carcinogenic to humans (Group 1) by the International Agency for Research on Cancer. This was based on the findings of epidemiological studies in Japan that occupationa...

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Detalhes bibliográficos
Publicado no:Toxicol Sci
Main Authors: Gi, Min, Fujioka, Masaki, Yamano, Shotaro, Shimomura, Eri, Ishii, Naomi, Kakehashi, Anna, Takeshita, Masanori, Wanibuchi, Hideki
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4833043/
https://ncbi.nlm.nih.gov/pubmed/25711234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfv045
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