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Evidence That the Capacity of Nongenotoxic Carcinogens to Induce Oxidative Stress Is Subject to Marked Variability

Many drugs and environmental chemicals which are not directly mutagenic have the capacity to increase the incidence of tumors in the liver and other tissues. For this reason, such compounds are known as nongenotoxic carcinogens. The mechanisms underlying their effects remain unclear; however, their...

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Détails bibliographiques
Publié dans:Toxicol Sci
Auteurs principaux: Henderson, Colin J., Cameron, Amy R., Chatham, Lynsey, Stanley, Lesley A., Wolf, Charles Roland
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2015
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4833039/
https://ncbi.nlm.nih.gov/pubmed/25690736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfv039
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