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A Mouse Strain Less Responsive to Dioxin-Induced Prostaglandin E(2) Synthesis Is Resistant to the Onset of Neonatal Hydronephrosis
Dioxin is a ubiquitous environmental pollutant that induces toxicity when bound to the aryl hydrocarbon receptor (AhR). Significant differences in susceptibility of mouse strains to dioxin toxicity are largely accounted for by the dissociation constant of binding to dioxins of AhR subtypes encoded b...
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Publié dans: | Toxicol Sci |
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Auteurs principaux: | , , , , |
Format: | Artigo |
Langue: | Inglês |
Publié: |
Oxford University Press
2014
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Sujets: | |
Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4833024/ https://ncbi.nlm.nih.gov/pubmed/25015655 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfu142 |
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