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Elevated hepatocyte growth factor expression as an autocrine c‐Met activation mechanism in acquired resistance to sorafenib in hepatocellular carcinoma cells

Hepatocellular carcinoma (HCC) is the most common type of primary liver cancer and the third leading cause of cancer‐related deaths worldwide. Limitations in HCC treatment result due to poor prognosis and resistance against traditional radiotherapy and chemotherapies. The multikinase inhibitor soraf...

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Dettagli Bibliografici
Pubblicato in:Cancer Sci
Autori principali: Firtina Karagonlar, Zeynep, Koc, Dogukan, Iscan, Evin, Erdal, Esra, Atabey, Neşe
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2016
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4832867/
https://ncbi.nlm.nih.gov/pubmed/26790028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12891
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