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Combined adjuvants of poly(I:C) plus LAG‐3‐Ig improve antitumor effects of tumor‐specific T cells, preventing their exhaustion

Therapeutic cancer vaccines are designed to treat cancer by boosting the endogenous immune system to fight against the cancer. In the development of clinically effective cancer vaccines, one of the most practical objectives is to identify adjuvants that are capable of optimizing the vaccine effects....

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Detalhes bibliográficos
Publicado no:Cancer Sci
Main Authors: Kano, Yosuke, Iguchi, Takahiro, Matsui, Hiroto, Adachi, Keishi, Sakoda, Yukimi, Miyakawa, Tomoya, Doi, Shun, Hazama, Shoichi, Nagano, Hiroaki, Ueyama, Yoshiya, Tamada, Koji
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4832865/
https://ncbi.nlm.nih.gov/pubmed/27079438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12861
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