Activation-Induced Cell Death of Dendritic Cells Is Dependent on Sphingosine Kinase 1

Sphingosine 1-phosphate (S1P) is an immune modulatory lipid mediator and has been implicated in numerous pathophysiological processes. S1P is produced by sphingosine kinase 1 (Sphk1) and Sphk2. Dendritic cells (DCs) are central for the direction of immune responses and crucially involved in autoimmu...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Schwiebs, Anja, Friesen, Olga, Katzy, Elisabeth, Ferreirós, Nerea, Pfeilschifter, Josef M., Radeke, Heinfried H.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2016
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4832589/
https://ncbi.nlm.nih.gov/pubmed/27148053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2016.00094
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