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Distinct expression patterns for type II topoisomerases IIA and IIB in the early foetal human telencephalon

TOP2A and TOP2B are type II topoisomerase enzymes that have important but distinct roles in DNA replication and RNA transcription. Recently, TOP2B has been implicated in the transcription of long genes in particular that play crucial roles in neural development and are susceptible to mutations contr...

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Vydáno v:J Anat
Hlavní autoři: Harkin, Lauren F., Gerrelli, Dianne, Gold Diaz, Diana C., Santos, Chloe, Alzu'bi, Ayman, Austin, Caroline A., Clowry, Gavin J.
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4832326/
https://ncbi.nlm.nih.gov/pubmed/26612825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/joa.12416
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