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Distinct expression patterns for type II topoisomerases IIA and IIB in the early foetal human telencephalon

TOP2A and TOP2B are type II topoisomerase enzymes that have important but distinct roles in DNA replication and RNA transcription. Recently, TOP2B has been implicated in the transcription of long genes in particular that play crucial roles in neural development and are susceptible to mutations contr...

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Detalhes bibliográficos
Publicado no:J Anat
Main Authors: Harkin, Lauren F., Gerrelli, Dianne, Gold Diaz, Diana C., Santos, Chloe, Alzu'bi, Ayman, Austin, Caroline A., Clowry, Gavin J.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4832326/
https://ncbi.nlm.nih.gov/pubmed/26612825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/joa.12416
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