The presence of prolines in the flanking region of an immunodominant HIV‐2 gag epitope influences the quality and quantity of the epitope generated

Both the recognition of HIV‐infected cells and the immunogenicity of candidate CTL vaccines depend on the presentation of a peptide epitope at the cell surface, which in turn depends on intracellular antigen processing. Differential antigen processing maybe responsible for the differences in both th...

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Bibliographische Detailangaben
Veröffentlicht in:Eur J Immunol
Hauptverfasser: Jallow, Sabelle, Leligdowicz, Aleksandra, Kramer, Holger B., Onyango, Clayton, Cotten, Matthew, Wright, Cynthia, Whittle, Hilton C., McMichael, Andrew, Dong, Tao, Kessler, Benedikt M., Rowland‐Jones, Sarah L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2015
Schlagworte:
Antigen Processing
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4832300/
https://ncbi.nlm.nih.gov/pubmed/26018465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201545451
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