The presence of prolines in the flanking region of an immunodominant HIV‐2 gag epitope influences the quality and quantity of the epitope generated

Both the recognition of HIV‐infected cells and the immunogenicity of candidate CTL vaccines depend on the presentation of a peptide epitope at the cell surface, which in turn depends on intracellular antigen processing. Differential antigen processing maybe responsible for the differences in both th...

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Dettagli Bibliografici
Pubblicato in:Eur J Immunol
Autori principali: Jallow, Sabelle, Leligdowicz, Aleksandra, Kramer, Holger B., Onyango, Clayton, Cotten, Matthew, Wright, Cynthia, Whittle, Hilton C., McMichael, Andrew, Dong, Tao, Kessler, Benedikt M., Rowland‐Jones, Sarah L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2015
Soggetti:
Antigen Processing
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4832300/
https://ncbi.nlm.nih.gov/pubmed/26018465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201545451
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