The presence of prolines in the flanking region of an immunodominant HIV‐2 gag epitope influences the quality and quantity of the epitope generated

Both the recognition of HIV‐infected cells and the immunogenicity of candidate CTL vaccines depend on the presentation of a peptide epitope at the cell surface, which in turn depends on intracellular antigen processing. Differential antigen processing maybe responsible for the differences in both th...

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Detalhes bibliográficos
Publicado no:Eur J Immunol
Main Authors: Jallow, Sabelle, Leligdowicz, Aleksandra, Kramer, Holger B., Onyango, Clayton, Cotten, Matthew, Wright, Cynthia, Whittle, Hilton C., McMichael, Andrew, Dong, Tao, Kessler, Benedikt M., Rowland‐Jones, Sarah L.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2015
Assuntos:
Antigen Processing
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4832300/
https://ncbi.nlm.nih.gov/pubmed/26018465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201545451
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