Four DNA methylation biomarkers in biliary brush samples accurately identify the presence of cholangiocarcinoma

Early detection of the highly aggressive malignancy cholangiocarcinoma (CCA) remains a challenge but has the potential to render the tumor curable by surgical removal. This study evaluates a biomarker panel for the diagnosis of CCA by DNA methylation analyses of biliary brush samples. The methylatio...

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Detalhes bibliográficos
Publicado no:Hepatology
Main Authors: Andresen, Kim, Boberg, Kirsten Muri, Vedeld, Hege Marie, Honne, Hilde, Jebsen, Peter, Hektoen, Merete, Wadsworth, Christopher A., Clausen, Ole Petter, Lundin, Knut E.A., Paulsen, Vemund, Foss, Aksel, Mathisen, Øystein, Aabakken, Lars, Schrumpf, Erik, Lothe, Ragnhild A., Lind, Guro E.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2015
Assuntos:
Hepatobiliary Malignancies
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4832263/
https://ncbi.nlm.nih.gov/pubmed/25644509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.27707
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