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The Parkinson Disease gene SNCA: Evolutionary and structural insights with pathological implication
After Alzheimer, Parkinson’s disease (PD) is the second most common neurodegenerative disorder. Alpha synuclein (SNCA) is deemed as a major component of Lewy bodies, a neuropathological feature of PD. Five point mutations in SNCA have been reported so far, responsible for autosomal dominant PD. This...
Enregistré dans:
| Publié dans: | Sci Rep |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4832246/ https://ncbi.nlm.nih.gov/pubmed/27080380 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep24475 |
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