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PFKFB3 Control of Cancer Growth by Responding to Circadian Clock Outputs

Circadian clock dysregulation promotes cancer growth. Here we show that PFKFB3, the gene that encodes for inducible 6-phosphofructo-2-kinase as an essential supporting enzyme of cancer cell survival through stimulating glycolysis, mediates circadian control of carcinogenesis. In patients with tongue...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Chen, Lili, Zhao, Jiajia, Tang, Qingming, Li, Honggui, Zhang, Chenguang, Yu, Ran, Zhao, Yan, Huo, Yuqing, Wu, Chaodong
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4832144/
https://ncbi.nlm.nih.gov/pubmed/27079271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep24324
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