Proteomic Characterization of Middle Ear Fluid Confirms Neutrophil Extracellular Traps as a Predominant Innate Immune Response in Chronic Otitis Media

BACKGROUND: Chronic Otitis Media (COM) is characterized by middle ear effusion (MEE) and conductive hearing loss. MEE reflect mucus hypersecretion, but global proteomic profiling of the mucosal components are limited. OBJECTIVE: This study aimed at characterizing the proteome of MEEs from children w...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Val, Stephanie, Poley, Marian, Brown, Kristy, Choi, Rachel, Jeong, Stephanie, Colberg-Poley, Annie, Rose, Mary C., Panchapakesan, Karuna C., Devaney, Joe C., Perez-Losada, Marcos, Preciado, Diego
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4831838/
https://ncbi.nlm.nih.gov/pubmed/27078692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0152865
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