Inhibition of Nonsmall Cell Lung Cancer Cell Migration by Protein Arginine Methyltransferase 1-small Hairpin RNA Through Inhibiting Epithelial-mesenchymal Transition, Extracellular Matrix Degradation, and Src Phosphorylation In Vitro

BACKGROUND: Protein arginine methyltransferases 1 (PRMT1) is over-expressed in a variety of cancers, including lung cancer, and is correlated with a poor prognosis of tumor development. This study aimed to investigate the role of PRMT1 in nonsmall cell lung cancer (NSCLC) migration in vitro. METHODS...

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Detalhes bibliográficos
Publicado no:Chin Med J (Engl)
Main Authors: Zhang, Ting, Cui, Ge, Yao, Yun-Liang, Guo, Yue, Wang, Qi-Chun, Li, Xi-Ning, Feng, Wen-Ming
Formato: Artigo
Idioma:Inglês
Publicado em: Medknow Publications & Media Pvt Ltd 2015
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4831548/
https://ncbi.nlm.nih.gov/pubmed/25947404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/0366-6999.156126
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