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The role of glioma stem cells in chemotherapy resistance and glioblastoma multiforme recurrence

Glioma stem cells (GSCs) constitute a slow-dividing, small population within a heterogeneous glioblastoma. They are able to self-renew, recapitulate a whole tumor, and differentiate into other specific GBM subpopulations. Therefore, they have been held responsible for malignant relapse after primary...

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Bibliografiske detaljer
Udgivet i:Expert Rev Neurother
Main Authors: Auffinger, Brenda, Spencer, Drew, Pytel, Peter, Ahmed, Atique U., Lesniak, Maciej S.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4830899/
https://ncbi.nlm.nih.gov/pubmed/26027432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1586/14737175.2015.1051968
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