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Wnt pathway antagonists, SFRP1, SFRP2, SOX17, and PPP2R2B, are methylated in gliomas and SFRP1 methylation predicts shorter survival

The deregulation of Wnt signaling is observed in various cancers, including gliomas, and might be related to the methylation of the genes encoding antagonists of this signaling pathway. The aim of the study was to assess the methylation status of the promoter regions of six Wnt negative regulators a...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:J Appl Genet
Asıl Yazarlar: Majchrzak-Celińska, Aleksandra, Słocińska, Marta, Barciszewska, Anna-Maria, Nowak, Stanisław, Baer-Dubowska, Wanda
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Springer Berlin Heidelberg 2015
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4830852/
https://ncbi.nlm.nih.gov/pubmed/26337424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13353-015-0312-7
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