Llwytho...

Structures and Energetics of Four Adjacent G·U Pairs That Stabilize an RNA Helix

Consecutive G·U base pairs inside RNA helices can be destabilizing while those at the ends of helices are thermodynamically stabilizing. To determine if this paradox could be explained by differences in base stacking, we determined the high-resolution (1.32 Å) crystal structure of (5’-GGUGGCUGUU-3&#...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Phys Chem B
Prif Awduron: Gu, Xiaobo, Mooers, Blaine H.M., Thomas, Leonard M., Malone, Joshua, Harris, Steven, Schroeder, Susan J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4830635/
https://ncbi.nlm.nih.gov/pubmed/26425937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jpcb.5b06970
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