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Structures and Energetics of Four Adjacent G·U Pairs That Stabilize an RNA Helix
Consecutive G·U base pairs inside RNA helices can be destabilizing while those at the ends of helices are thermodynamically stabilizing. To determine if this paradox could be explained by differences in base stacking, we determined the high-resolution (1.32 Å) crystal structure of (5’-GGUGGCUGUU-3&#...
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| Publicado no: | J Phys Chem B |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4830635/ https://ncbi.nlm.nih.gov/pubmed/26425937 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jpcb.5b06970 |
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