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Role of Double-Strand Break End-Tethering during Gene Conversion in Saccharomyces cerevisiae

Correct repair of DNA double-strand breaks (DSBs) is critical for maintaining genome stability. Whereas gene conversion (GC)-mediated repair is mostly error-free, repair by break-induced replication (BIR) is associated with non-reciprocal translocations and loss of heterozygosity. We have previously...

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Detalles Bibliográficos
Publicado en:PLoS Genet
Main Authors: Jain, Suvi, Sugawara, Neal, Haber, James E.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4830573/
https://ncbi.nlm.nih.gov/pubmed/27074148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005976
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