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Effect of pioglitazone treatment in a patient with secondary multiple sclerosis
BACKGROUND: Ligands of the peroxisome proliferator-activated receptor-gamma (PPARγ) induce apoptosis in activated T-lymphocytes and exert anti-inflammatory effects in glial cells. Preclinical studies have shown that the thiazolidinedione pioglitazone, an FDA-approved PPARγ agonist used to treat type...
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Main Authors: | , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
BioMed Central
2004
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC483056/ https://ncbi.nlm.nih.gov/pubmed/15285799 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-1-3 |
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