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Entamoeba histolytica Cysteine Proteinase 5 Evokes Mucin Exocytosis from Colonic Goblet Cells via αvβ3 Integrin

Critical to the pathogenesis of intestinal amebiasis, Entamoeba histolytica (Eh) induces mucus hypersecretion and degrades the colonic mucus layer at the site of invasion. The parasite component(s) responsible for hypersecretion are poorly defined, as are regulators of mucin secretion within the hos...

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Bibliographic Details
Published in:PLoS Pathog
Main Authors: Cornick, Steve, Moreau, France, Chadee, Kris
Format: Artigo
Language:Inglês
Published: Public Library of Science 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4830554/
https://ncbi.nlm.nih.gov/pubmed/27073869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005579
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