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Regulation of Apoptosis by HER2 in Breast Cancer
HER2 is a trans-membrane receptor tyrosine kinase that activates multiple growth-promoting signaling pathways including PI3K-AKT and Ras-MAPK. Dysregulation of HER2 is a frequent occurrence in breast cancer that is associated with poor patient outcomes. A primary function of HER2 is suppressing apop...
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| Publicat a: | J Carcinog Mutagen |
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| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4830426/ https://ncbi.nlm.nih.gov/pubmed/27088047 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4172/2157-2518.S7-003 |
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