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Fitness of Escherichia coli mutants with reduced susceptibility to tigecycline

OBJECTIVES: The objective of this study was to determine the fitness of Escherichia coli mutants with reduced susceptibility to tigecycline after exposure to adverse conditions in vitro and in vivo. METHODS: Survival in response to low pH, bile salts, oxidative stress and human serum was examined fo...

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Veröffentlicht in:J Antimicrob Chemother
Hauptverfasser: Linkevicius, Marius, Anderssen, Jytte Mark, Sandegren, Linus, Andersson, Dan I.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4830415/
https://ncbi.nlm.nih.gov/pubmed/26851608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dkv486
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