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Enzyme-Instructed Self-Assembly of Small d-Peptides as a Multiple-Step Process for Selectively Killing Cancer Cells

[Image: see text] Selective inhibition of cancer cells remains a challenge in chemotherapy. Here we report the molecular and cellular validation of enzyme-instructed self-assembly (EISA) as a multiple step process for selectively killing cancer cells that overexpress alkaline phosphatases (ALPs). We...

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Pubblicato in:J Am Chem Soc
Autori principali: Zhou, Jie, Du, Xuewen, Yamagata, Natsuko, Xu, Bing
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Chemical Society 2016
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4830347/
https://ncbi.nlm.nih.gov/pubmed/26966844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.5b13541
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