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Predicting drug target interactions using meta-path-based semantic network analysis

BACKGROUND: In the context of drug discovery, drug target interactions (DTIs) can be predicted based on observed topological features of a semantic network across the chemical and biological space. In a semantic network, the types of the nodes and links are different. In order to take into account t...

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Veröffentlicht in:BMC Bioinformatics
Hauptverfasser: Fu, Gang, Ding, Ying, Seal, Abhik, Chen, Bin, Sun, Yizhou, Bolton, Evan
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2016
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4830032/
https://ncbi.nlm.nih.gov/pubmed/27071755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-016-1005-x
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