Profibrotic role of WNT10A via TGF-β signaling in idiopathic pulmonary fibrosis

BACKGROUND: WNT/β-catenin signaling plays an important role in the pathogenesis of idiopathic pulmonary fibrosis (IPF); however, the role of WNT10A via transforming growth factor (TGF)-β signaling remains unclear. METHODS: We evaluated the expression of WNT10A and TGF-β in bleomycin (BLM)-treated mi...

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Bibliographic Details
Published in:Respir Res
Main Authors: Oda, Keishi, Yatera, Kazuhiro, Izumi, Hiroto, Ishimoto, Hiroshi, Yamada, Sohsuke, Nakao, Hiroyuki, Hanaka, Tetsuya, Ogoshi, Takaaki, Noguchi, Shingo, Mukae, Hiroshi
Format: Artigo
Language:Inglês
Published: BioMed Central 2016
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4830023/
https://ncbi.nlm.nih.gov/pubmed/27071460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-016-0357-0
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