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Differential expression of the epigenetic methylation-related protein DNMT1 by breast cancer molecular subtype and stromal histology

BACKGROUND: We assessed the expression of methylation-related proteins 5-meC, DNMT1, and ISL-1 in breast cancer and evaluated their relationship to clinicopathological factors. METHODS: Immunohistochemical staining for ER, PR, HER-2, Ki-67, 5-meC, DNMT1, and ISL-1 were performed on 348 breast cancer...

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Detalhes bibliográficos
Publicado no:J Transl Med
Main Authors: Shin, Eunah, Lee, YuKyung, Koo, Ja Seung
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4830007/
https://ncbi.nlm.nih.gov/pubmed/27071379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-016-0840-x
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