Integrated genomic characterization of IDH1-mutant glioma malignant progression

Gliomas represent approximately 30% of all central nervous system tumors and 80% of malignant brain tumors(1). To understand the molecular mechanisms underlying the malignant progression of low-grade gliomas with mutations in IDH1 (encoding isocitrate dehydrogenase 1), we studied paired tumor sample...

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Gepubliceerd in:Nat Genet
Hoofdauteurs: Bai, Hanwen, Harmanci, Akdes Serin, Erson-Omay, E Zeynep, Li, Jie, Coşkun, Süleyman, Simon, Matthias, Krischek, Boris, Özduman, Koray, Omay, S Bülent, Sorensen, Eric A, Turcan, Şevin, Bakırcığlu, Mehmet, Carrión-Grant, Geneive, Murray, Phillip B, Clark, Victoria E, Ercan-Sencicek, A Gulhan, Knight, James, Sencar, Leman, Altınok, Selin, Kaulen, Leon D, Gülez, Burcu, Timmer, Marco, Schramm, Johannes, Mishra-Gorur, Ketu, Henegariu, Octavian, Moliterno, Jennifer, Louvi, Angeliki, Chan, Timothy A, Tannheimer, Stacey L, Pamir, M Necmettin, Vortmeyer, Alexander O, Bilguvar, Kaya, Yasuno, Katsuhito, Günel, Murat
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2015
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4829945/
https://ncbi.nlm.nih.gov/pubmed/26618343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.3457
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