Elevated Ratio of Th17 Cell-Derived Th1 Cells (CD161(+)Th1 Cells) to CD161(+)Th17 Cells in Peripheral Blood of Early-Onset Rheumatoid Arthritis Patients

Rheumatoid arthritis (RA) is a chronic inflammatory disease characterized by the destruction of articular cartilage and bone with elevated levels of proinflammatory cytokines. It has been reported that IL-17 and Th17 cells play important roles in the pathogenesis of RA. Recently, plasticity in helpe...

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Bibliographic Details
Published in:Biomed Res Int
Main Authors: Kotake, Shigeru, Nanke, Yuki, Yago, Toru, Kawamoto, Manabu, Kobashigawa, Tsuyoshi, Yamanaka, Hisashi
Format: Artigo
Language:Inglês
Published: Hindawi Publishing Corporation 2016
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4829689/
https://ncbi.nlm.nih.gov/pubmed/27123445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/4186027
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