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Sequestration of host metabolism by an intracellular pathogen

For intracellular pathogens, residence in a vacuole provides a shelter against cytosolic host defense to the cost of limited access to nutrients. The human pathogen Chlamydia trachomatis grows in a glycogen-rich vacuole. How this large polymer accumulates there is unknown. We reveal that host glycog...

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Veröffentlicht in:eLife
Hauptverfasser: Gehre, Lena, Gorgette, Olivier, Perrinet, Stéphanie, Prevost, Marie-Christine, Ducatez, Mathieu, Giebel, Amanda M, Nelson, David E, Ball, Steven G, Subtil, Agathe
Format: Artigo
Sprache:Inglês
Veröffentlicht: eLife Sciences Publications, Ltd 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4829429/
https://ncbi.nlm.nih.gov/pubmed/26981769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.12552
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