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RGD peptide-modified adenovirus expressing hepatocyte growth factor and X-linked inhibitor of apoptosis improves islet transplantation

BACKGROUND: Islet transplantation has the potential for treating type I diabetes; however, its widespread clinical application is limited by the massive apoptotic cell death and poor revascularization of transplanted islet grafts. METHODS: We constructed a surface-modified adenoviral vector with RGD...

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Bibliografische gegevens
Gepubliceerd in:J Gene Med
Hoofdauteurs: Wu, Hao, Yoon, A.-Rum, Li, Feng, Yun, Chae-Ok, Mahato, Ram I.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2011
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4829356/
https://ncbi.nlm.nih.gov/pubmed/22095898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jgm.1626
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