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Role of lysine binding residues in the global folding of the lysC riboswitch

Riboswitches regulate gene expression by rearranging their structure upon metabolite binding. The lysine-sensing lysC riboswitch is a rare example of an RNA aptamer organized around a 5-way helical junction in which ligand binding is performed exclusively through nucleotides located at the junction...

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Detalhes bibliográficos
Publicado no:RNA Biol
Main Authors: Smith-Peter, Erich, Lamontagne, Anne-Marie, Lafontaine, Daniel A
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4829333/
https://ncbi.nlm.nih.gov/pubmed/26403229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15476286.2015.1094603
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