Application of surface plasmon resonance imaging to monitoring G protein-coupled receptor signaling and its modulation in a heterologous expression system

BACKGROUND: G protein-coupled receptors (GPCRs) are ubiquitous surface proteins mediating various biological responses and thus, important targets for therapeutic drugs. GPCRs individually produce their own signaling as well as modulate the signaling of other GPCRs. Real-time observation of GPCR sig...

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Detalhes bibliográficos
Publicado no:BMC Biotechnol
Main Authors: Nonobe, Yuki, Yokoyama, Tomoki, Kamikubo, Yuji, Yoshida, Sho, Hisajima, Nozomi, Shinohara, Hiroaki, Shiraishi, Yuki, Sakurai, Takashi, Tabata, Toshihide
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Methodology Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4828886/
https://ncbi.nlm.nih.gov/pubmed/27068216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12896-016-0266-9
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