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Single time point comparisons in longitudinal randomized controlled trials: power and bias in the presence of missing data

BACKGROUND: The primary analysis in a longitudinal randomized controlled trial is sometimes a comparison of arms at a single time point. While a two-sample t-test is often used, missing data are common in longitudinal studies and decreases power by reducing sample size. Mixed models for repeated mea...

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Detalhes bibliográficos
Publicado no:BMC Med Res Methodol
Main Authors: Ashbeck, Erin L., Bell, Melanie L.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4828848/
https://ncbi.nlm.nih.gov/pubmed/27068578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12874-016-0144-0
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