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Predictive value of BRCA1 expression on the efficacy of chemotherapy based on anti-microtubule agents: a pooled analysis across different malignancies and agents

BACKGROUND: Breast cancer susceptibility gene 1 (BRCA1) expression has been suggested as a predictor in anti-neoplastic treatment with anti-microtubule agents. However, the existing evidence is conflicting. Consulting the literature, we sought to examine the true impact of BRCA1 expression on the ef...

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Detalhes bibliográficos
Publicado no:Ann Transl Med
Main Authors: He, Qihua, Zhang, Mingzhe, Zhang, Jianrong, Zhong, Shengyi, Liu, Yang, Shen, Jianfei, He, Jiaxi, Jiang, Long, Yang, Chenglin, Zeng, Yuan, Guo, Minzhang, Chen, Xuewei, He, Jianxing, Liang, Wenhua
Formato: Artigo
Idioma:Inglês
Publicado em: AME Publishing Company 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4828752/
https://ncbi.nlm.nih.gov/pubmed/27127763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/atm.2016.03.27
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