Dynamic interaction of SARAF with STIM1 and Orai1 to modulate store-operated calcium entry

Ca(2+) influx by store-operated Ca(2+) channels is a major mechanism for intracellular Ca(2+) homeostasis and cellular function. Here we present evidence for the dynamic interaction between the SOCE-associated regulatory factor (SARAF), STIM1 and Orai1. SARAF overexpression attenuated SOCE and the S...

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Udgivet i:Sci Rep
Main Authors: Albarran, Letizia, Lopez, Jose J., Amor, Nidhal Ben, Martin-Cano, Francisco E., Berna-Erro, Alejandro, Smani, Tarik, Salido, Gines M., Rosado, Juan A.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4828706/
https://ncbi.nlm.nih.gov/pubmed/27068144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep24452
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